Mast cell myositis: a new feature of allergic asthma?
نویسندگان
چکیده
منابع مشابه
Mast Cells in Allergic Asthma and Beyond
Mast cells have been regarded for a long time as effector cells in IgE mediated type I reactions and in host defence against parasites. However, they are resident in all environmental exposed tissues and express a wide variety of receptors, suggesting that these cells can also function as sentinels in innate immune responses. Indeed, studies have demonstrated an important role of mast cells dur...
متن کاملIncreased Mast Cell Density and Airway Responses to Allergic and Non-Allergic Stimuli in a Sheep Model of Chronic Asthma
BACKGROUND Increased mast cell (MC) density and changes in their distribution in airway tissues is thought to contribute significantly to the pathophysiology of asthma. However, the time sequence for these changes and how they impact small airway function in asthma is not fully understood. The aim of the current study was to characterise temporal changes in airway MC density and correlate these...
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Recent physiological and pharmacological studies have indicated the potential importance of tryptase, the major protein component in mast cells, in inflammatory diseases (especially asthma). Being released at inflammatory sites after the activation of mast cells, tryptase is capable of causing bronchohyperresponsiveness and infiltration of eosinophils, neutrophils, etc. in animal airways. The m...
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19 cats were nper-sensitized to allergic asthma by receiving a concomitant spray ang injection of ovalbumin (10% fresh egg-white in normal saline) every other days for four weeks.then animals were anesthetized and left femoral artery cannulation performed to record atrerial pressure and take blood samples.left femoral vein was cannulated to infuse nutritional fluids and grugs as needed.trachea ...
متن کاملGeneral overview of fungal allergic asthma
Asthma is a complicated disorder, whose prevalence has increased over the past few decades.Asthma is characterized by infiltration of inflammatory leukocytes along with enhancedproinflammatory cytokines and chemokines. Fungi are now far more widely being considered as thedominant extrinsic trigger for asthma. Fungi are linked to the severity of asthma in many ways. Somedifferences between studi...
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ژورنال
عنوان ژورنال: Allergy
سال: 2005
ISSN: 0105-4538,1398-9995
DOI: 10.1111/j.1398-9995.2005.00898.x